Detalhe da pesquisa
1.
Hypoxia drives CD39-dependent suppressor function in exhausted T cells to limit antitumor immunity.
Nat Immunol
; 24(2): 267-279, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36543958
2.
Mitochondrial stress induced by continuous stimulation under hypoxia rapidly drives T cell exhaustion.
Nat Immunol
; 22(2): 205-215, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33398183
3.
Germinal center B cells selectively oxidize fatty acids for energy while conducting minimal glycolysis.
Nat Immunol
; 21(3): 331-342, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32066950
4.
Oncolytic Viruses Engineered to Enforce Leptin Expression Reprogram Tumor-Infiltrating T Cell Metabolism and Promote Tumor Clearance.
Immunity
; 51(3): 548-560.e4, 2019 09 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-31471106
5.
Treg Cells Promote the SREBP1-Dependent Metabolic Fitness of Tumor-Promoting Macrophages via Repression of CD8+ T Cell-Derived Interferon-γ.
Immunity
; 51(2): 381-397.e6, 2019 08 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-31350177
6.
Metabolic support of tumour-infiltrating regulatory T cells by lactic acid.
Nature
; 591(7851): 645-651, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33589820
7.
The Tumor Microenvironment Represses T Cell Mitochondrial Biogenesis to Drive Intratumoral T Cell Metabolic Insufficiency and Dysfunction.
Immunity
; 45(2): 374-88, 2016 08 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-27496732
8.
The Lysophosphatidylcholine Transporter MFSD2A Is Essential for CD8+ Memory T Cell Maintenance and Secondary Response to Infection.
J Immunol
; 203(1): 117-126, 2019 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31127034
9.
The Tumor Microenvironment Represses T Cell Mitochondrial Biogenesis to Drive Intratumoral T Cell Metabolic Insufficiency and Dysfunction.
Immunity
; 45(3): 701-703, 2016 09 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-27653602
10.
Cutting Edge: Murine Mast Cells Rapidly Modulate Metabolic Pathways Essential for Distinct Effector Functions.
J Immunol
; 198(2): 640-644, 2017 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27974455
11.
Cutting Edge: Differential Regulation of PTEN by TCR, Akt, and FoxO1 Controls CD4+ T Cell Fate Decisions.
J Immunol
; 194(10): 4615-9, 2015 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25855357
12.
Metabolic reprogramming via an engineered PGC-1α improves human chimeric antigen receptor T-cell therapy against solid tumors.
J Immunother Cancer
; 11(3)2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36914208
13.
The effect of opioids on the efficacy of immunotherapy in recurrent/metastatic squamous cell carcinoma of the head and neck.
Oral Oncol
; 140: 106363, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36963232
14.
Excess Dietary Sugar Alters Colonocyte Metabolism and Impairs the Proliferative Response to Damage.
Cell Mol Gastroenterol Hepatol
; 16(2): 287-316, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37172822
15.
Obesity Is Associated with Altered Tumor Metabolism in Metastatic Melanoma.
Clin Cancer Res
; 29(1): 154-164, 2023 01 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36166093
16.
Analyzing Melanoma Cell Oxygen Consumption and Extracellular Acidification Rates Using Seahorse Technology.
Methods Mol Biol
; 2265: 81-89, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33704707
17.
Tumor hypoxia is associated with resistance to PD-1 blockade in squamous cell carcinoma of the head and neck.
J Immunother Cancer
; 9(5)2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33986123
18.
Checkpoint molecules coordinately restrain hyperactivated effector T cells in the tumor microenvironment.
Oncoimmunology
; 9(1): 1708064, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32076578
19.
Tumor-Derived α-Fetoprotein Suppresses Fatty Acid Metabolism and Oxidative Phosphorylation in Dendritic Cells.
Cancer Immunol Res
; 7(6): 1001-1012, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30988028
20.
mTORC2 Deficiency Alters the Metabolic Profile of Conventional Dendritic Cells.
Front Immunol
; 10: 1451, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31338091